Partial Thromboplastin Time

Laboratory Methodologic Approach in Prolonged Activated Partial Thromboplastin Time Test

The pathological activated partial thromboplastin time test is a data that we can find in all clinical laboratories routinely. The hemato-coagulative clinical case here reported aims to point out how the laboratory can provide a correct diagnosis by methodological rational setting and, consequently, carry out an appropriate therapy, or reassure the patient that the pathological data will not ca...

The partial thromboplastin (cephalin) time test.

Nine partial thromboplastin (cephalin) reagents have been compared in a parallel investigation of groups of patients on ;long-term' anticoagulants, a group with moderate haemophilia, and patients on heparin infusion. Results with the seven commercial reagents and a human cephalin extract have been correlated with those of a specially prepared and standardized reference preparation of human brai...

Evaluation of Antiphospholipid Antibodies and Activated Partial Thromboplastin Time in Women with Adverse Outcome of Pregnancy

Adverse outcome of pregnancy is a potentially dangerous complication of conception and affects 15-20% of pregnancies. According to recent studies increased level of blood antiphospholipids antibodies, if accompanied by predisposing factors, can be an adverse event in human pregnancy. The aim of the present study was to compare the maternal serum levels of anticardiolipin and antiphosphatidyl se...

A further face of the partial thromboplastin time APTT.

Effect of warfarin on activated partial thromboplastin time.

BACKGROUND The activated partial thromboplastin time (APTT) is used to adjust heparin sodium dosage. However, warfarin sodium is often administered concomitantly with heparin and may also affect the APTT and, therefore, heparin dose. We performed a prospective cohort study to quantify the effect of warfarin on the APTT in patients who are being treated with heparin. METHODS Serial assays of A...